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Alan Franciscus
Editor-in-Chief
HCV Advocate
HBV Advocate

Thursday, April 18, 2013

Tenofovir/emtricitabine topped other regimens for patients coinfected with HIV, HBV

Combining tenofovir disoproxil fumarate with emtricitabine resulted in greater long-term hepatitis B virus suppression than other treatments among patients coinfected with HIV and HBV in a recent study.
In a multinational longitudinal study, researchers collected data from 165 HIV/HBV-coinfected patients from the United States, Australia and Thailand. The majority of the cohort (90.3%) either used or planned to use highly active antiretroviral therapy (HAART) within 1 year of study initiation. Patient follow-up occurred every 6 months for a median of 2.8 years, resulting in 1,015 study visits. Using logistic regression, researchers determined factors associated with detectable HBV DNA (characterized as greater than 357 IU/mL).

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