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Alan Franciscus
HCV Advocate

Sunday, September 2, 2012

Triple Infection with HBV Promotes HCV Clearance in People with HIV

Competition between hepatitis B virus (HBV) and hepatitis C virus (HCV) in HIV positive people with triple infection appears to promote spontaneous HCV clearance, but lower CD4 T-cell counts and greater liver inflammation reduce the likelihood of clearance, Chinese researchers reported at the XIX International AIDS Conference (AIDS 2012) last month in Washington, DC.

Prior studies have shown that HBV and HCV seem to interfere with each other's replication, usually to the advantage of HBV. Yuan Dong from Fudan University in Shanghai and colleagues looked at viral interactions, liver inflammation, viral genotypes, and other factors that might affect spontaneous clearance in individuals with HBV/HCV/HIV triple infection.


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