Competition between hepatitis B virus (HBV) and hepatitis C virus (HCV)
in HIV positive people with triple infection appears to promote
spontaneous HCV clearance, but lower CD4 T-cell counts and greater liver
inflammation reduce the likelihood of clearance, Chinese researchers
reported at the XIX International AIDS Conference (AIDS 2012) last month
in Washington, DC.
Prior studies have shown that HBV and HCV seem to interfere with each
other's replication, usually to the advantage of HBV. Yuan Dong from
Fudan University in Shanghai and colleagues looked at viral
interactions, liver inflammation, viral genotypes, and other factors
that might affect spontaneous clearance in individuals with HBV/HCV/HIV
triple infection.
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