Welcome to HCV Advocate’s hepatitis blog. The intent of this blog is to keep our website audience up-to-date on information about hepatitis and to answer some of our web site and training audience questions. People are encouraged to submit questions and post comments.
For more information on how to use this blog click here, the HCV drug pipeline click here, and for more information on HCV clinical trials click here
Drugs in Development / Clinical Trials—Updated October 13, 2014
Monday, October 20, 2014
The study also reports that people who share injection equipment, such as cookers, cottons and water are 4 times more likely to be infected with hepatitis C than people who do not share injection equipment. Last week I spoke with Jon Zibbell, researcher with the Division of Viral Hepatitis at the Centers for Disease Control and lead author on the report, to ask about the science behind these extraordinary findings.
—Alan Franciscus, Editor-in-Chief
Blood-to-blood contact transmits hepatitis C. In Egypt the most common transmission routes include:
- Sharing needles and works for injection drug use (medical, traditional practices and recreational use),
- Receiving a blood transfusion or an organ transplant,
- Dental practices,
- Medical care from local informal health providers and centers.
- Unsterilized medical and dental instruments,
- Gloves used on multiple patients,
- Blood spills not cleaned up,
- One-use vials used on more than one patient,
- Used syringes
Egypt has a national plan in place to train medical staff and the population (urban and rural) about blood safety. Egypt is a poor country that has many cultural practices that will need to be addressed before blood safety practices can change.
In 2013, there were 153,000 deaths recorded—33,000 related to HCV; 120,000 deaths for all-cause mortality. HCV can be a contributing factor for non-HCV related deaths so the actual number of deaths related to HCV might be higher.
The Ministry of Health treats 50,000 patients a year; Health Insurance Organization treats 10,000; 5,000 patients paid cash for treatment.
His interest in a hearing comes as the expense of these medicines helps fuel a national debate over the rising cost of prescription drugs. New hepatitis C treatments, in particular, have caused a ruckus, because they promise cure rates exceeding 90%, which is prompting a sudden surge in prescribing – and subsequent concerns over the effect on insurance budgets.
The team at SN dug deeper. “The tear fluids are tested in labs for various ophthalmological procedures, which is how they found the virus there. There is a high possibility that it could spread to their bodies or in the case of them donating their eyes, pass on to the person receiving the transplant,” explained Dr Samuel J K Abraham, director of the Nichi-in Centre for Regenerative Medicine — a Japanese-Indian collaboration.
To find the answers to why this happened, researchers got to work and used a synthetic polymer scaffold, developed in Waseda University in Japan, to create the world’s second 3D lab culture of the Hep C Virus.
—Alan Franciscus, Editor-in-Chief
When an infection does occur in humans, the virus can be spread in several ways to others. Ebola is spread through direct contact (through broken skin or mucous membranes in, for example, the eyes, nose, or mouth) with:
- Blood or body fluids (including but not limited to urine, saliva, sweat, feces, vomit, breast milk, and semen) of a person who is sick with Ebola
- Objects (like needles and syringes) that have been contaminated with the virus
- Infected animals
- Ebola is not spread through the air or by water, or in general, by food. However, in Africa, Ebola may be spread as a result of handling bushmeat (wild animals hunted for food) and contact with infected bats. There is no evidence that mosquitos or other insects can transmit the Ebola virus. Only mammals (for example, humans, bats, monkeys, and apes) have shown the ability to become infected with and spread Ebola virus.
- The Flu kills from 3,000 to 49,000 a year: Get the annual flu shot; wash your hands regularly for at least 20 seconds after you use the toilet or come into contact with germs;
- Smoking cigarettes kills more than 400,000 deaths a year: hink about quitting or cutting back
- Automobile accidents kill more than 32,000 people a year: Wear a safety belt, don’t drive under the influence; drive defensively
Sunday, October 19, 2014
Right now the disease everyone's paying attention to is Ebola, a virus that presents with flu-like systems but can have serious, and often fatal, consequences. But putting things into context Ebola hasn't become a huge global killer. Thus far the death toll has crossed 4,000. This is a saddening figure, but it pales in comparison to the annual death toll from HIV/AIDS or tuberculosis, for example.
180 million have this disease, but few know it!
There is, however, another deadly disease in existence that, based on data from the World Health Organization, affects an estimated 180 million people, or 3% of the world's population. Though it may not be as lethal as Ebola in terms of how quickly it kills it victims, this global disease can, in its chronic state, lead to liver damage, liver disease, liver cancer, or even death. Within just the U.S., it's a disease that claims 15,000 lives annually.